Colon lesion induced by the intake of nonsteroidal anti-inflammatory drugs (NSAIDs) (NSAID-induced colopathy) is a serious but poorly understood condition.Objective: to investigate the incidence, clinical and endoscopic characteristics of NSAID-induced colopathy, as well as the efficacy BATH TRAY of sulfasalazine in this pathology.Subjects and meth
A preformulative study was conducted to produce and characterize ethosomes for the transdermal delivery of gossypin.This plant-derived compound possesses many pharmacological properties, including antitumoral potential.Ethosome Ornaments dispersions were designed as transdermal delivery systems for gossypin, employing two different production proce
Comorbid depressive disorders confound the diagnosis Canes and therapy of schizophrenia.Using a murine model incorporating both MK801 and chronic unpredictable mild stress exposures, we successfully replicated both psychosis and depression.Ex vivo patch clamp recordings and in vivo calcium imaging demonstrated impaired neural activity in the prefro
ABSTRACT: In the greater inland Jianghan Basin of South China, three salt depressions are lacking accurate geological times, of which Canes Jiangling Depression is the largest.Evaporites are important records of paleoclimate, however, the geological ages of evaporates are very difficult to be determined because often evaporates have scare macrofoss